using jquery and telerik ajax manager I was able to add a dirty check to the imput controls.

1. ascx page with dynamic controls loading in a place holder.

2. Add jQuery code to add the change function.  but code on bottom of ascx page.
 
<script type="text/javascript">
     var _isDirty = false;
     $(":input").change(function () {
         setDirty();
     });

     // checks to see if form is dirty before leaving page.
     //close, update and cancel buttons will set the isDirty to 0 to avoid alert .
     $(window).bind('beforeunload', function () {
         checkSave();
     }
    );

     var isDirty;
     isDirty = 0;

     function setDirty() {
         isDirty = 1;
     }

     function checkSave() {
         var sSave;
         if (isDirty == 1) {
             sSave = window.confirm("You have some changes that have NOT been saved. Click OK to save now or CANCEL to continue without saving.");
             if (sSave == true) {
                 $find("<%= RadAjaxManager1.ClientID %>").ajaxRequest("Save");
               
             } else {
                 return true;
             }
         }
     }

    </script>

3 telerik ajax manager

 <telerik:RadAjaxManager ID="RadAjaxManager1" runat="server"
        onajaxrequest="RadAjaxManager1_AjaxRequest">
</telerik:RadAjaxManager>

4. cs code behind for ajax request

 protected void RadAjaxManager1_AjaxRequest(object sender, Telerik.Web.UI.AjaxRequestEventArgs e)
        {
            if (e.Argument == "Save")
            {
                SaveData();
            }
        }

5. page load to set some buttons to set isDirty back to 0
   protected void Page_Load(object sender, EventArgs e)
        {
        
            ibUpdate.Attributes.Add("onclick", "isDirty = 0;");
            ibCancel.Attributes.Add("onclick", "isDirty = 0;");        
        }